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| 卵巢癌的二线化疗 | |
| 引用本文： | 闻强（综述）,朱笕青（审校）. 卵巢癌的二线化疗[J]. 国外医学(计划生育．生殖健康分册), 2009, 28(4): 263-265,268 |
| 作者姓名： | 闻强（综述） 朱笕青（审校） |
| 作者单位： | 浙江省肿瘤医院妇瘤科; |
| 摘 要： | 超过80%的晚期卵巢癌患者因复发需要接受二线化疗。目前多项大型随机对照试验表明,对于铂类敏感患者,以铂类为基础的联合化疗,如紫杉醇+卡铂或吉西他滨+卡铂,在有效率及改善生存方面优于铂类单药化疗,可作为首选。而对于铂类耐药患者,无论采用何种化疗,效果均不理想,临床上一般采用不良反应较小、使用方便的单药化疗作为姑息性治疗,联合化疗的价值有待更多随机对照试验证明。 |
| 关 键 词： | 卵巢肿瘤 复发 药物疗法 抗肿瘤联合化疗方案 抗药性 |
Second-line Chemotherapy of Ovarian Cancer |
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| WEN Qiang,ZHU Jian-qing. Gynecological Oncology. Second-line Chemotherapy of Ovarian Cancer[J]. , 2009, 28(4): 263-265,268 | |
| Authors: | WEN Qiang ZHU Jian-qing. Gynecological Oncology |
| Affiliation: | WEN Qiang,ZHU Jian-qing. Gynecological Oncology Department of Zhejiang Provincial Cancer Hospital,Hangzhou 310022,China |
| Abstract: | More than 80% of patients with advanced ovarian cancer need second-line chemotherapy for the recurrence. A number of large scale randomized controlled trials have confirmed that the platinum -based combination chemotherapy,such as paclitaxel combined with carboplatin or gemcitabine combined with carboplatin,can be used as the best options for its superiorities on effectiveness and survival improvement in platinum-sensitive patients compared with platinum monotherapy. However,the effects of any kinds of chem... |
| Keywords: | Ovarian neoplasm Recurrence Drug therapy Antineoplastic combination chemotherapy protocols Drug resistance |
| 本文献已被 CNKI 维普 等数据库收录！ | |