反复卵泡未破裂黄素化患者56个周期治疗体会

目的探讨卵泡未破裂黄素化综合征导致不孕的治疗方法。方法对2008年1月年至2010年3月间在不孕不育门诊就诊的患者进行检查,选择反复卵泡未破裂黄素化者共78个病例,随机分为A、B两组,A组进行西医联合的治疗,共56个周期;B组仅给予枸橼酸氯米芬胶囊或尿促性腺素促排卵治疗,共56个周期。结果 A组56个周期中,发生排卵41例,排卵率73.21%,妊娠15例,妊娠率38.46%,流产1例,流产率2.56%;B组56个周期中,发生排卵23例,排卵率41.07%,妊娠5例,妊娠率12.82%,流产1例,流产率2.56%。两组排卵率、妊娠率比较有显著性差异(P<0.05)。结论西医联合治疗可改善某些反复卵泡未破裂黄素化患者反复卵泡黄素化状况并达到妊娠目的。

56 Cases on treatment cycle of recurrent unruptured ovarian fiberation

Objective To investigate the treatment methods of infertility caused by luteinized unruptured follicle syndrome. Methods Seventy - eight cases of recurrent luteinized unruptured follicle syndrome were determined from those who visited the infertility clinic of the hospital between January 2008 and March 2010. The patients were randomly divided into two groups. Group A was treated by traditional Chinese medicine and Western medicine with 56 cycles; group B was given clomiphene citrate or HMG ovulation induction treatment with 56cycles. Results For group A, during the 56 treatment cycles, ovulation occurred in 41 cases, resulting in the ovulation rate of 73.21%, pregnancy in 15 cases, preg- nancy rate38.46% and abortion in 1 case, the abortion rate 2.56% ; for group B, during the 56 treatment cycles, ovulation occurred in 23 cases, ovulation rate 41.07%, pregnancy in 5 cases, pregnancy rate 12.82% and abortion in 1 case, abortion rate 2.56%. There were significant differences in ovulation rate and pregnancy rate between the two groups （ P 〈 0. 05 ）. Conclusion The integrative treatment of traditional Chinese medicine and Western medicine can improve recurrent follicular luteinizing condition and help to achieve pregnancy.