清灵定眩汤治疗椎-基底动脉供血不足眩晕患者的临床观察

目的 探讨清灵定眩汤治疗椎-基底动脉供血不足眩晕（VBIV）临床疗效。方法 在中西医常规对症、支持基础上分别加用西比灵（对照组19例）及清灵定眩汤（治疗组20例）治疗2周，比较两组临床疗效及复发情况。结果 治疗组临床疗效、复发率、症状评分、血液流变学及经颅多普勒指标改善均优于对照组（P〈0．05或P〈0．01）。结论 清灵定眩汤对VBIV有明显的治疗作用，而改善微循环和降低血液黏度可能是其治疗学机制之一。

Clinical Observation on Qingling Dingxuan Decoction in Treating Vertigo Cause by Insufficient Blood-supply of Ventebrobasilar Artery

ObjectiveTo observe the therapeutic effect of Qingling Dingxuan Decoction (QDD) on vertigo caused by insufficient blood-supply of ventebrobasilar artery (IBVA). Methods Thirty-nine patients were divided into the flunarizine group (n=19) and the QDD group (n=20) treated with respective medicine on the base of routine treatment with Chinese and Western medicine. The clinical efficacy and recurrent rate were observed and compared. Results Compared with those in the flunarizine group, clinical curative effect was better, recurrent rate lower, symptom score higher, hemorheological parameters and transcranial doppler indexes were improved more significant in the QDD group (P<0.01 or P<0.05). Conclusion QDD had obvious therapeutic effect on IBVA. Improvement of microcirculation and reduction of blood viscosity may be one of the therapeutical mechanisms.