非痴呆性血管性认知功能障碍患者脑梗死病变特点的分析

①目的探讨非痴呆性血管性认知功能障碍（VCIND）患者梗死病变特点与认知功能损害的关系。②方法对VCIND患者进行6～24个月的随访,依据血管性痴呆的诊断标准最终将患者分为仍为VCIND组和进展为血管性痴呆（VD）组,分析比较两组患者在随访前临床确诊为VCIND时在梗死数量及梗死部位方面所具有的特征,以探讨促使VCIND患者进展为VD的影响因素。③结果进展为VD组患者总梗死数量多于仍处于VCIND组,在进展为VD组中,额区、丘脑、基底节区梗死数量均高于仍处于VCIND组。额区、丘脑、基底节区的梗死和脑白质稀疏均可加重VCIND患者进展为VD。④结论研究梗死数量和梗死部位的特点对预测VCIND患者进展为VD的风险有重大意义。

Analysis of infarct lesion charaters for vascular cognitive impairment no dementia

Objective To investigate relationship between infarct lesion charaters of vascular cognitive impairment no dementia and cognitive functional lesion.Methods Follow up VCIND patients for six to twentyfour months,according to Vascular Dementia diagnostic criteria,all the patients were divided into 2 groups,remained VCIND groups and progressed VD groups.Analyzed characteristic of infarct quantity and infarct position between the two groups,when they were clinical definited VCIND.And investigated the influential factor of VCIND changed into VD.Results Not only Total infarct quantity in progressed VD group were more than that in the remained VCIND group,but also the infarct quantity of frontal region、thalamus region、basal ganglia region were more than that in the remained VCIND group.The infarction of frontal region、thalamus region、basal ganglia region and Leukoaraiosis can both aggratate VCIND to become into VD.Conclusion Research the characteristic of infarct quantity and infarct position was more important to predict the risks of VCIND becamed into VD.