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Distribution of mouse mammary tumor virus-related sequences does not correlate with the taxonomic position of their hosts |
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| Authors: | Tanya V. Golovkina Andrei T. Tikhonenko Nikita S. Vassetzky III Boris I. Sheftel Andrei V. Gudkov |
| Affiliation: | (1) Laboratory of Molecular Genetics, Institute of Carcinogenesis, National Cancer Research Center, USSR Academy of Medical Sciences, Moscow, USSR;(2) Department of Virology, Faculty of Biology, State University of Moscow, Moscow, USSR;(3) Institute of Animal Evolutionary Morphology and Ecology, USSR Academy of Sciences, Moscow, USSR |
| Abstract: | Sequences (MRS) distantly related to mouse mammary tumor virus (MMTV) were found in genomes of a wide range of mammalian species using blot hybridization. The number of MRS copies and the degree of their homology with the hybridization probe varied and did not correlate with the taxonomic position of the species. Nevertheless, within a genus the set of MRS was species specific and reflected the taxonomic relation between the species. MRS were also found in avian genomes and the degree of their homology did not correlate with the taxonomic position of the species either. The origin and distribution of MRS is discussed on the basis of the authors' and published data. |
| Keywords: | mouse mammary tumor virus MMTV related sequences retrovirus evolution blot hybridization |
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