A rapid method for the inactivation of virus infectivity prior to assay for interferons |
| |
| Authors: | A D Barrett N Hunt N J Dimmock |
| |
| Affiliation: | 1. Department of Biological Sciences, University of Warwick, Coventry CV4 7AL U.K.;2. Heinrich P Institut für Experimentelle Virologie and Immunologie, Universität Hamburg, Martinistrasse 52, D-20 Hamburg 20, F.R.G. |
| |
| Abstract: | ![]()
Virus infectivity in samples of culture medium or suspensions of animal tissue which are required for interferon assay can be rapidly and conveniently inactivated by overnight incubation with beta-propiolactone (BPL). As BPL hydrolyses spontaneously samples can be assayed with no further treatment. BPL does not affect the interfering activity of alpha, beta or gamma mouse interferons. |
| |
| Keywords: | beta-propiolactone inactivation of virus assay of interferons α, β, γ |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
