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Step‐wise loss of antidepressant effectiveness with repeated antidepressant trials in bipolar II depression |
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| Authors: | Jay D Amsterdam Lorenzo Lorenzo‐Luaces Robert J DeRubeis |
| Affiliation: | 1. Depression Research Unit, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA;2. Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA;3. Methods to Improve Diagnostic Assessment and Services (MIDAS) Project, Brown University, Providence, RI, USA |
| Abstract: | |
| Keywords: | antidepressant bipolar disorder depression drug tolerance lithium loss of response SNRI SSRI tachyphylaxis treatment‐resistant depression venlafaxine |