局部点滴双氯灭痛或狄奥宁治疗人工晶体术后瞳孔膜的实验研究

目的：通过用双氯灭痛或狄奥宁滴液，观察对人工晶体植入术后瞳孔膜的防治作用。方法：24只成年纯系新西兰白兔的48只眼，随机分为3组：双氯灭痛治疗组（A组J）、狄奥宁治疗组（B组）和空白对照组（C组）。48只兔眼均行晶体囊外摘除及后房型人工晶体植入术；术后1，3，5，7，14，21，30d定量动态观察人工晶体表现瞳孔膜的情况。结果：A 组的瞳孔膜低于B，C组（P＜0．05）；B组瞳孔膜低于C组（P＜0．05）。结论：双氯灭痛与狄奥宁滴眼均能有效治疗人工晶体植入术后瞳孔膜；双氯灭痛的疗效优于狄奥宁。

Experimental study on using diclofenac sodium or dionine topically to treat fibrinous membrane after intraocular lens implantation]

OBJECTIVE: To find a reasonable method for treating and preventing fibrinous membrane after intraocular lens (IOL) implantation by using diclofenac sodium or dionine topically. METHODS: Forty-eight eyes of twenty-four adult pure bred New Zealand rabbits were divided into three groups randomly. Group A: rabits received diclofenac sodium eyedrops; Group B: rabbits received dionine eyedrops; Group C: controlled. All the eyes received lens extraction combined with posterior chamber intraocular lens implantation. The fibrinous membrane was observed after 1, 3, 5, 7, 14, 21 and 30 days postoperatively. RESULTS: The fibrinous membran in Group A was less than that of Group B and Group C, (P < 0.05); the difference between group B and group C on fibrinous membrance was also statistically significant (P < 0.05). CONCLUSION: The study suggests that both diclofenac sodium and the dionine eyedrops can treat fibrinous membrane after IOL implantation. The effect of diclofenac sodium is better than that of dionine.