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| ST段抬高型心肌梗死患者纤维蛋白原和D-二聚体的相关研究 | |
| 引用本文： | 李勇,吕树铮,孟康,马临安,李志忠,郭路芬. ST段抬高型心肌梗死患者纤维蛋白原和D-二聚体的相关研究[J]. 临床心血管病杂志, 2010, 26(1) |
| 作者姓名： | 李勇 吕树铮 孟康 马临安 李志忠 郭路芬 |
| 作者单位： | 1. 北京市心肺血管病研究所,首都医科大学附属北京安贞医院心肺血管抢救中心,北京,100029 2. 北京市心肺血管病研究所,首都医科大学附属北京安贞医院心内科 |
| 基金项目： | 北京市科委重大科技支持项目(No:D0906006040191) |
| 摘 要： | 目的:探讨ST段抬高型心肌梗死(STEMI)患者与冠状动脉造影阴性的对照组纤维蛋白原和D-二聚体含量的差异。方法:选取2007-01-2008-08间STEMI并行直接冠状动脉介入治疗术(PCI)患者161例。同时选取冠状动脉造影阴性的对照组161例,比较2组间纤维蛋白原和D-二聚体含量。结果:STEMI患者血浆纤维蛋白原含量(2.47±0.89)g/L低于对照者(2.79±0.69)g/L,差异有统计学意义(t=-3.62,P<0.01)。STE-MI患者D-二聚体含量(μg/L)的平方根(10.96±5.66)高于对照者(9.13±5.04),差异有统计学意义(t=3.07,P<0.01)。STEMI患者血浆D-二聚体含量(μg/L)与纤维蛋白原含量(g/L)比值的平方根(7.52±4.56)高于对照者(5.63±3.29),差异有统计学意义(t=4.26,P<0.01)。结论:STEMI患者的纤维蛋白原低于冠状动脉造影阴性的对照组,D-二聚体高于对照组,提示在STEMI急性期存在急性血栓形成和继发性纤溶。 |
| 关 键 词： | 冠状动脉疾病 ST段抬高型心肌梗死 纤维蛋白原 D-二聚体 |
The relationship between plasma fibrinogen and D-dimer in patients with ST-elevation myocardial infarction |
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| LI Yong,LV Shuzheng,MENG Kang,MA linan,LI Zhizhong,GUO Lufen. The relationship between plasma fibrinogen and D-dimer in patients with ST-elevation myocardial infarction[J]. Journal of Clinical Cardiology, 2010, 26(1) | |
| Authors: | LI Yong LV Shuzheng MENG Kang MA linan LI Zhizhong GUO Lufen |
| Affiliation: | 1Rescue Center/a>;2Department of Cardiology Beijing Institute of Heart/a>;Lung & Blood Vessel Diseases/a>;Beijing Anzhen Hospital Affiliated of Capital Medical University/a>;Beijing 100029/a>;China |
| Abstract: | Objective:To compare concentration of fibrinogen and D-dimer between patients with ST-elevation myocardial infarction(STEMI) and normal angiography of coronary artery.Methods:Patients (n=161) with STEMI were studied and patients (n=161) with normal coronary arteriograms were selected as a control,Beijing Anzhen Hospital,from Jan.2007 to Aug.2008. There were 131 males and 30 females in STEMI group and 131 males and 30 females in control group too.Plasma concentration of fibrinogen and D-dimer were compared b... |
| Keywords: | coronary disease ST-elevation myocardial infarction fibrinogen D-dimer |
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