| 当归醇沉物及其中性组份体外对巨噬细胞分泌TNF-α和IL-1的影响 |
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| 引用本文： | 奚瑾磊,彭仁琇,王智勇.当归醇沉物及其中性组份体外对巨噬细胞分泌TNF-α和IL-1的影响[J].中草药,2002,33(5):437-439. |
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| 作者姓名： | 奚瑾磊 彭仁琇 王智勇 |
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| 作者单位： | 武汉大学医学院药理教研室,湖北,武汉,430071 |
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| 摘 要： | 目的观察当归醇沉物(ESA)及其中性组分(ESA-1)体外对小鼠腹腔巨噬细胞分泌TNF-α、IL-1的影响.方法L929细胞株细胞毒法测TNF-α;L929细胞增殖法测IL-1.结果ESA、ESA-1与小鼠腹腔巨噬细胞(Mφ)共同培养可显著增强其TNF-α、IL-1的分泌.在5～20μg/mL浓度范围,ESA的这种作用呈剂量依赖性;ESA-1虽有明显的作用,但未表现出剂量依赖.结论当归醇沉物及其中性组分体外可增强小鼠腹腔巨噬细胞分泌TNF-α、IL-1.
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| 关 键 词： | 当归醇沉物 巨噬细胞 TNF-α |
| 收稿时间： | 9/4/2001 12:00:00 AM |
Effects of ethanol sediments from tuber of Angelica sinensis and its litmusless component on secreting TNF-α and IL-1 of macrophages in vitro |
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| XI Jin lei,PENG Ren xiu and WANG Zhi yong.Effects of ethanol sediments from tuber of Angelica sinensis and its litmusless component on secreting TNF-α and IL-1 of macrophages in vitro[J].Chinese Traditional and Herbal Drugs,2002,33(5):437-439. |
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| Authors: | XI Jin lei PENG Ren xiu and WANG Zhi yong |
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| Institution: | Department of Pharmacology, Medical College of Wuhan University, Wuhan Hubei 430071, China;Department of Pharmacology, Medical College of Wuhan University, Wuhan Hubei 430071, China;Department of Pharmacology, Medical College of Wuhan University, Wuhan Hubei 430071, China |
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| Abstract: | |
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| Keywords: | IL-1 |
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