中西医结合治疗强直性脊柱炎65例临床观察

目的:观察中西医结合治疗强直性脊柱炎的临床疗效。方法:入选强直性脊柱炎患者随机分为治疗组(65例)和对照组(58例)。对照组使用非甾体类消炎药、慢作用药,治疗组在对照组基础上加用中医综合疗法。分别于治疗后3个月、6个月观察治疗前后临床症状、关节功能活动程度、扩胸试验、Schober’s氏试验、指地试验、枕墙距的变化;实验室检查血沉(ESR)、C-反应蛋白(CRP)。结果:治疗后3个月、6个月,2组各观察指标与治疗前比较,差异有统计学意义(P<0.05),2组间总有效率比较差异有统计学意义(P<0.05),且治疗组不良反应发生率、复发率低于对照组,差异有统计学意义(P<0.05)。结论:中西医结合治疗强直性脊柱炎能明显改善强直性脊柱炎患者的症状、体征,提高患者的生活质量。

A Clinical Observation on 65 Cases of Ankylosis Spondylitis Treated with Integrated Traditional Chinese and Western Medicine Therapy

Objective:To observe the clinical curative effects of integrated traditional Chinese and western medicine therapy in treating ankylosing spondylitis(AS).Methods:One hundred and twenty-three patients with AS were randomly divided into 2 groups,65 cases in treatment group and 58 cases in control group.Patients in the control group were administrated with the nonsteroidal anti-inflammatory drugs and slow-acting antirheumatic drugs,while the treatment group received integrated traditional Chinese medicine therapy based on the treatment in control group.The curative effects of the patients were evaluated from the following aspects of clinical symptoms,ranges of motion,chest expansion test,schober test,finger ground test,occiput to wall distance,ESR,and CRP.Results:Three months and six months after the treatment,there was statistical difference in the curative effects compared with before-after study(P<0.05).The total effective rate in treatment group and in control group with significant difference,and the incidence of adverse reactions,recurrence rate were statistically significant difference between the two groups(P<0.05).Conclusion:The method of integrated traditional Chinese and western medicine therapy can improve patients with AS in the clinical symptoms,signs and the quality of life.