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Effects of ezetimibe and/or simvastatin on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase gene expression: a randomized trial in healthy men
Authors:Gouni-Berthold Ioanna  Berthold Heiner K  Gylling Helena  Hallikainen Maarit  Giannakidou Eleni  Stier Sebastian  Ko Yon  Patel Dilip  Soutar Anne K  Seedorf Udo  Mantzoros Christos S  Plat Jogchum  Krone Wilhelm
Institution:

aDepartment of Internal Medicine II, University of Cologne, Kerpener Street 62, 50937 Cologne, Germany

bMedical Faculty, Clinical Pharmacology, University of Bonn, Bonn, Germany

cDepartment of Clinical Nutrition, University of Kuopio and Kuopio University Hospital, Kuopio, Finland

dMedical Policlinic, University of Bonn, Bonn, Germany

eMRC Clinical Sciences Centre, Hammersmith Hospital, London, United Kingdom

fLeibniz Institute for Arteriosclerosis Research, University of Münster, Münster, Germany

gDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

hDepartment of Human Biology, Maastricht University, Maastricht, The Netherlands

Abstract:
Keywords:Ezetimibe  Simvastatin  LDL receptor  HMG-CoA reductase  Gene expression  PCSK9  NPC1L1
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