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肝癌肿瘤细胞与外周血淋巴细胞体外药敏试验的相关性研究
引用本文:覃理灵,廖维甲,梅铭惠. 肝癌肿瘤细胞与外周血淋巴细胞体外药敏试验的相关性研究[J]. 中国实验诊断学, 2007, 11(6): 795-797
作者姓名:覃理灵  廖维甲  梅铭惠
作者单位:桂林医学院附属医院,肝胆外科研究室,广西,桂林,541001
摘    要:目的 利用肝癌患者淋巴细胞与癌细胞进行化疗药物敏感测定。方法 取肝癌患者外周血和手术切取肝癌标本利用MTT法,体外检测32例患者淋巴细胞和癌细胞对10种化疗药物的敏感性。结果 淋巴细胞平均抑制率与肝癌细胞平均抑制率无明显差异(P〉0.05)。结论 肝癌患者淋巴细胞化疗药敏检测对不可切肝癌选择化疗药物具有重要参考价值。

关 键 词:MTT法  肝癌  淋巴细胞  药敏试验
文章编号:1007-4287(2007)06-0795-03
修稿时间:2006-05-07

To study the correlation between in vitro chemosensitivity of peripheral blood lymphocytes and tumor cell of hepatocellular carcinoma patients
QIN Li-ling,LIAO Wei-jia,MEI Ming-hui. To study the correlation between in vitro chemosensitivity of peripheral blood lymphocytes and tumor cell of hepatocellular carcinoma patients[J]. Chinese Journal of Laboratory Diagnosis, 2007, 11(6): 795-797
Authors:QIN Li-ling  LIAO Wei-jia  MEI Ming-hui
Affiliation:The Affliated Hospital of Guilin Medical College, Guilin 541001, China
Abstract:Objective Through assessing between in vitro sensitivity of peripheral blood lymphocyte and tumor cells.Methods the sensitivity of 10 kinds of anticancer drugs in the hepatocellular carcinoma patients peripheral blood lymphocyte and operate tumor specimen of 32cases with in vitro were tested by the MTT method.Results the average inhibiting rate in between peripheral blood lymphocyte and tumor cells were no difference obvious(P>0.05).Conclusion the detection of chemosensitivity of peripheral blood lymphocyte in no operate hepatocellular carcinoma patients exerts important referential value to choosing of chemotherapeutic drugs.
Keywords:MTT assay   hepatacellularcarcinoma   lymphocyte   chemosemitivity test
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