| 颅脑损伤病人早期凝血功能与损伤程度及预后的相关性研究 |
| |
| 引用本文： | 武宇鼎,鞠海涛.颅脑损伤病人早期凝血功能与损伤程度及预后的相关性研究[J].内蒙古医学院学报,2011,33(1):25-28. |
| |
| 作者姓名： | 武宇鼎 鞠海涛 |
| |
| 作者单位： | 内蒙古医学院附属人民医院神经外科,内蒙古呼和浩特,010020 |
| |
| 基金项目： | 国家黎介寿院士肠道屏障研究项目 |
| |
| 摘 要： | 目的：探讨颅脑损伤（TBI）病人凝血功能的变化及其与颅脑损伤程度与预后的关系。方法：依据格拉斯哥昏迷评分（GCS）将95例颅脑损伤病人分为轻、中、重度损伤三组,测定其入院时的凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、血小板计数（PLT）和D-二聚体（DD）的水平,并与30例健康体检者（对照组）作对照。治疗1mo后依据牛津残障评分（OHC）对所有病人的预后进行评估,并将其分为预后良好组和预后不良组,比较两组病人的PT、APTT、PLT和DD水平。结果：随着伤情的加重,TBI病人的PT、APTT和DD水平依次增加,而PLT依次下降,差异均有统计学差异（P〈0.01）。与预后良好病人,预后不良病人的PT、APTT和DD水平明显增高,而PLT水平明显降低,均有统计学差异（P〈0.01）。结论：TBI病人凝血功能与颅脑损伤程度和预后密切相关,可用于病情评估和预后判断。
|
| 关 键 词： | 颅脑损伤 凝血功能 预后 |
THE STUDY OF CORRELATION AMONG EARLY COAGULATION FUNCTION AND SEVERITY AND PROGNOSIS IN TRAUMATIC BRAIN INJURY |
| |
| WU Yu - ding,JU Hai - tao.THE STUDY OF CORRELATION AMONG EARLY COAGULATION FUNCTION AND SEVERITY AND PROGNOSIS IN TRAUMATIC BRAIN INJURY[J].Acta Academiae Medicinae Neimongol,2011,33(1):25-28. |
| |
| Authors: | WU Yu - ding JU Hai - tao |
| |
| Institution: | WU Yu-ding,JU Hai-tao(Department of Neurosurgery,Affiliated Hospital,Inner Monogolia Medical College,Hohhot 010020 China) |
| |
| Abstract: | Objective: To explore the correlation among early coagulation function,severity and prognosis in traumatic brain injury(TBI).Methods: A total of 95 TBI cases were divided into mild,moderate and severe injury groups based on GCS,and the levels of PT,APTT,PLT and DD were measured on admission,compared with those in 30 healthy controls(control group).After one-month treatment,Oxford handicap scale was employed to assess the prognosis of all the TBI patients,based on that all the TBI patients were divided into ... |
| |
| Keywords: | Traumatic brain injury Coagulation function Prognosis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
