| 耐万古霉素肠球菌的耐药机制及耐药基因调控的研究进展 |
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| 引用本文： | 姚杰,徐元宏. 耐万古霉素肠球菌的耐药机制及耐药基因调控的研究进展[J]. 国外医药(抗生素分册), 2010, 31(1): 24-28 |
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| 作者姓名： | 姚杰 徐元宏 |
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| 作者单位： | 安徽医科大学第一附属医院检验科,合肥230032;安徽医科大学第二附属医院检验科,合肥,230601;安徽医科大学第一附属医院检验科,合肥,230032 |
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| 摘 要： | 耐万古霉素肠球菌现已成为重要的医院感染病原菌，其对万古霉素耐药方式分为获得性耐药和先天性耐药，其中获得性耐药的类型包括VanA、VanB、VanD、VanG和VanE，先天性耐药的类型有VanC1／C2／C3。本文针对耐万古霉素肠球菌的耐药机制及其耐药基因的调控进行综述，以供参考。
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| 关 键 词： | 肠球菌属 万古霉素 耐药机制 |
Research Progress of the Drug Resistant Mechanism and the Resistance Gene Regulation of Vancomycin-resistant Enterococcus |
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| YAO Jie,XU Yuan-hong. Research Progress of the Drug Resistant Mechanism and the Resistance Gene Regulation of Vancomycin-resistant Enterococcus[J]. world notes on antibiotics, 2010, 31(1): 24-28 |
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| Authors: | YAO Jie XU Yuan-hong |
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| Affiliation: | YAO Jie, XU Yuan-hong (1 Department of Clinical Laboratory, the First Affiliated Hospital of Anhui Medical University, Hefei 230032, China; 2 Department of Clinical Laboratory, the Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China) |
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| Abstract: | Vancomycin-resistant Enterococcus have become important pathogens of nosocomial infection. The mechanisms of vancomycin-resistance can be divided into natural resistance and acquired resistance. The genes associated with acquired drug resistance include VanA, VanB, VanD, VanG and VanE; while VanC1/C2/C3 are involved with natural drug resistance. This view focuses on the recent progress of the drug resistance mechanisms and the resistance gene regulation of vancomycin-resistant Enterococcus. |
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| Keywords: | Enterococcus vancomycin drug resistant mechanism |
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