婴幼儿急性下呼吸道感染呼吸道病毒抗原检测分析

目的：了解婴幼儿急性下呼吸道感染常见病毒的感染发生率及探讨病毒感染与性别的关系。方法：在婴幼儿急性下呼吸道感染的病例中随机抽取男性和女性患儿各1 000例,取其鼻咽深部的刷检物进行直接免疫荧光法检测。结果：2 000例急性下呼吸道感染的婴幼儿中七项呼吸道病毒检出率为27.45%（549/2 000）,其中以（呼吸道合胞病毒）RSV为主,其次分别为（副流感病毒1型）PIV-1、（副流感病毒3型）PIV-3、（腺病毒）ADV、（甲型流感病毒）IFVA、（副流感病毒2型）PIV-2、（乙型流感病毒）IFV-B。其中PIV-3男性与女性感染率比较（χ2=4.465,P〈0.05）,两者差异有统计学意义。结论：引起婴幼儿急性下呼吸道感染的七项病毒中,以RSV为主。并且除PIV-3外,其他六种病毒感染均无性别差异。

Detection and Analysis of the Virus in Young Children with Acute Lower Respiratory Tract Infection

Objective：To study the incidence of the common virus infection in young children with acute lower respiratory tract infection and investigate the relationship between the infection and gender.Methods：Using random sampling,we collected 1 000 male and female patients（young children）with acute lower respiratory tract infection,respectively.Nasopharyngeal wabs were taken during respiratory episodes for direct immunofluorescence test.Results：In the 2 000 patients with acute lower respiratory tract infection,the prevalence of seven respiratory virus was 27.45%（549/2 000）.Among these virus,RSV was the most predominant one,followed by PIV-1,PIV-3,ADV,IFV-A,PIV,IFV-B.The incidence of PIV-3infection between male and female patients were significantly different（χ^2=4.465,P0.05）.Conclusion：Among the seven respiratory virus,RSV was the predominant virus leading to lower respiratory tract infection of young children.Besides,except for PIV-3,there were no association between other six virus and gender.