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An efficacy analysis of posterior fossa decompression techniques in the treatment of Chiari malformation with associated syringomyelia
Authors:Yundong Zhang  Nan Zhang  Huijia Qiu  Ji Zhou  Peiliang Li  Mingliang Ren  Guangjian Shen  Lichao Chen  Chun Zhou  Donghong Yang  Yingchun Liu  Ying Mao  Xiaohong Gu  Yao Zhao
Affiliation:aDepartment of Neurosurgery, Research Institute of Surgery, DaPing Hospital, Third Military Medical University, 10 Changjiang Zhi Road, Chongqing 400042, China;bDepartment of Geriatrics, Research Institute of Surgery, DaPing Hospital, Third Military Medical University, 10 Changjiang Zhi Road, Chongqing 400042, China;cDepartment of Neurosurgery, HuaShan Hospital, Shanghai Medical College, FuDan University, 12 Wulumuqi Zhong Road, Shanghai 200040, China
Abstract:
A retrospective study of the efficacy of posterior fossa decompression (PFD) was carried out in 132 patients with Chiari malformation (CM) with associated syringomyelia (SM). Of these 132 patients, 69 received extended PFD (large craniotomy group), and the other 63 patients received only local PFD (small craniotomy group). At the short-term postoperative evaluation (1–4 weeks) the extended PFD appeared to be more effective than the local PFD (p < 0.05). However, there was no significant difference in long-term analysis (6 months–11 years) (p > 0.05). In the large craniotomy group, there was no difference between the short-term and long-term efficacy (p > 0.05). However, in the small craniotomy group, long-term efficacy clearly improved (p < 0.05). Furthermore, patients who had undergone local PFD exhibited more obvious radiological improvement of SM (p < 0.05) and fewer postoperative complications compared to patients undergoing extended PFD (p < 0.05). Therefore, local PFD is preferable for the surgical treatment of CM with associated SM.
Keywords:Chiari malformation   Extent of craniotomy   Posterior fossa decompression   Syringomyelia
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