结直肠癌肿瘤干细胞标志物的研究进展 |
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引用本文: | 马法库,刘斌. 结直肠癌肿瘤干细胞标志物的研究进展[J]. 肿瘤研究与临床, 2014, 0(8): 571-573 |
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作者姓名: | 马法库 刘斌 |
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作者单位: | 兰州军区兰州总医院病理科;兰州大学基础医学院病理研究所,730050 |
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基金项目: | 甘肃省自然科学基金(096RJZA096) |
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摘 要: | 近年来,肿瘤干细胞(CSC)学说得到越来越多的支持,识别CSC的关键就是寻找干细胞的表面特异性标志物.结直肠癌CSC的相关研究不断取得进展,文章综述了近几年发现的比较公认的干细胞标志物CD44、SOX9、ALDH1和OCT-4等的研究进展及其与结直肠癌的关系.
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关 键 词: | 结直肠肿瘤 肿瘤干细胞标志物 |
Research progress of cancer stem cell markers in colorectal cancer |
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Affiliation: | Ma Faku(Department of Pathology, Lanzhou General Hospital, Lanzhou Command, Lanzhou 730050 ,China) |
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Abstract: | Now that the cancer stem cell (CSC) theory has been verified for many scholars.The key to the identification of CSC is to find specific stem cell surface markers.The study of colorectal CSC continues to show progress.In recent years,many stem cell markers were discovered,such as CD44,SOX9,ALDH1,OCT-4 and so on.This article will discuss the relationship between those makers and colorectal cancer. |
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Keywords: | Colorectal neoplasms Cancer stem cell marker |
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