胎儿骨移植修复良性骨肿瘤术后骨缺损

目的　总结胎儿骨移植修复良性骨肿瘤术后骨缺损的临床应用效果。方法　1994年1月～1999年6月，应用经酒精处理后的胎儿骨移植修复148例良性骨肿瘤术后骨缺损，其中骨囊肿63例，骨纤维异常增生症42例，骨巨细胞瘤26例，内生软骨瘤17例。骨缺损最大3.5cm×10.0cm，最小0.5cm×1.0cm。结果　148例良性骨肿瘤术后骨缺损修复均于3～12个月达骨性愈合，平均愈合时间为6.2个月。随访1～6年，平均14个月，肿瘤无复发，无局部及全身反应。结论　胎儿骨作为良性骨肿瘤术后的骨缺损修复材料无明显组织反应，临床效果满意。

REPAIR OF BONE DEFECT WITH BENIGN TUMOR BY EMBRYONIC BONE TRANSPLANTATION

OBJECTIVE: To evaluate the clinical results of repair of bone defect by embryonic bone transplantation. METHODS: From January 1994 to June 1999, 148 cases of bone defect were repaired by embryonic bone transplantation following alcohol treatment, there were 63 cases with bone cyst, 42 cases with fibrous dysplasia of bone, 26 cases with giant cell tumor of bone, and 17 cases with enchondroma among them. The maximal bone defect was 3.5 cm x 10.0 cm, while the minimal defect was 0.5 cm x 1.0 cm. RESULTS: All of those bone defect with benign tumor were bone union used by embryonic bone transplantation after 3 months to 1 year of operation, the average healing course was 6.2 months, followed up 1 to 6 years, averaged 14 months, no tumor recurrence and no obvious local or system response were observed. CONCLUSION: Embryonic bone can be used as a good repairing material of postoperative bone defect of benign tumors, the clinical results are satisfactory.