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| 血浆脂肪细胞型脂肪酸结合蛋白水平与急性脑梗死的关系 | |
| 引用本文： | 赵琪,邹大进. 血浆脂肪细胞型脂肪酸结合蛋白水平与急性脑梗死的关系[J]. 上海医学, 2010, 33(3) |
| 作者姓名： | 赵琪 邹大进 |
| 作者单位： | 第二军医大学附属长海医院内分泌科,上海,200433 |
| 摘 要： | 目的 探讨急性脑梗死患者血浆脂肪细胞型脂肪酸结合蛋白(A-FABP)的水平及其与相关危险因素的关系.方法 测定81例急性脑梗死患者(脑梗死组)及20名健康者(对照组)的A-FABP水平,分析其与高血压、高血脂、高血糖等危险因素的关系.根据其伴有的危险因素数目的 多少,将脑梗死组患者分为4个亚组:单纯脑梗死(A)、脑梗死伴1个危险因素(B)、脑梗死伴2个危险因素(C)、脑梗死伴3个或3个以上危险因素(D)亚组,分析A-FABP与相关危险因素的关系.结果 脑梗死组与对照组间空腹血糖、空腹胰岛素、胆固醇、高密度脂蛋白的差异均无统计学意义(P值均0.05),而脑梗死组的年龄、收缩压、舒张压、体质指数、三酰甘油、低密度脂蛋白、A-FABP均显著高于对照组(P值分别<0.05、0.01).A、B、C、D亚组的血浆A-FABP水平分别为(15.99±1.72)、(13.83±5.12)、(25.04±3.10)、(34.84±7.15)ng/mL,除A亚组与B亚组间的差异无统计学意义外(P0.05),其他各亚组间的差异均有统计学意义(P值分别<0.05、0.01).结论 脑梗死患者的血浆A-FABP水平明显高于健康者,随着危险因素的增多,脑梗死患者的A-FABP水平升高. |
| 关 键 词： | 脑梗死 脂肪酸结合蛋白 动脉硬化 危险因素 |
Relationship between plasma level of fatty acid-binding protein and acute cerebral infarction |
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| ZHAO Qi,ZOU Dajin. Relationship between plasma level of fatty acid-binding protein and acute cerebral infarction[J]. Shanghai Medical Journal, 2010, 33(3) | |
| Authors: | ZHAO Qi ZOU Dajin |
| Affiliation: | ZHAO Qi,ZOU Dajin. Department of Endocrinology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China |
| Abstract: | Objective To study the plasma level of adipocyte fatty acid binding protein (A-FABP) in patients with acute cerebral infarction and the related risk factors. Methods The levels of plasma fatty acid-binding protein were measured in 81 patients with acute cerebral infarction (CI group) and 20 healthy subjects(control group), and their relationship with high blood pressure, high cholesterol, high blood sugar, and other risk factors were analyzed. According to the number of risk factors that presented, the pati... |
| Keywords: | Cerebral infarction Fatty acid binding protein Atherosclerosis Risk factors |
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