声学密度定量技术与冠状动脉造影术的对比研究

目的：探讨声学密度定量（AD）技术评价正常、狭窄及闭塞血管支配区域心肌的组织特征。方法：对疑诊冠心病的64例患者，根据冠状动脉造影结果将192支冠状动脉分组：正常组（A组）、狭窄组（B组）、闭塞组（C组），检测其相应血管支配区域心肌的背向散射积分参数。结果：与A组相比，B组心肌的背向散射积分的标化值（IBS％）增高；而背向散射积分周期变化幅度（CVIB）减小；C组心肌的IBS％增高更明显；CVIB减小也更明显。且14支闭塞血管支配区域心肌的CVIB曲线与正常节段呈反向，N－delay在B组及C组明显延长，同一参数组间比较差异均有显著性（P＜0．01），结论：AD技术能客观反映正常，狭窄及闭塞冠状动脉脉供血区域心域心肌的不同组织特性变化，对鉴别冠心病不同病变心肌的灌流特征具有一定的诊断意义。

A Comparative Study on Acoustic Densitometry (AD) Technique and Coronary Artery Angiography

Objective: To evaluate the value of acoustic densitometry (AD) technique in detecting the changes of tissue characterization of myocardibyum which supplied normal, stenosis, and occluded artery. Methods: One hundred and ninety-two coronary arteries from 64 patients were divided into normal (group A), stenosis (group B), and occluded groups (group C). Myocardia of three groups were measured with AD parameters. Results: IBS% increased and CVIB decreased in myocardium in group B compared with that in group A(P<0.01), and were significantly higher than that in group C(P<0.01). CVIB curve of 14 segments supplied by occluded coronary artery appeared reverse change. N-delay prolonged significantly in groups B and C (P<0.01). Conclusion: AD technology can detect the change of tissue characterization in myocardium supplied by normal, stenosis, and excluded artery. The index is useful in identification of myocardial disease with coronary artery disease.