| 联合应用血必净与钠洛酮干预重症胸腹损伤急性肝细胞功能损害的效果 |
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| 引用本文： | 李志伟,郭雅琼,王文军,徐旭,董浩,代文光,王树龙,马之嘉,付芳.联合应用血必净与钠洛酮干预重症胸腹损伤急性肝细胞功能损害的效果[J].医学研究杂志,2015,44(2):156-158,116. |
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| 作者姓名： | 李志伟 郭雅琼 王文军 徐旭 董浩 代文光 王树龙 马之嘉 付芳 |
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| 作者单位： | 中国人民解放军第253医院急诊科,呼和浩特,010051 |
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| 摘 要： | 目的探讨联合应用血必净(XBJ)、钠洛酮(NX)干预重症胸腹损伤急性肝细胞功能损害的效果。方法以2009年1月~2013年6月在笔者医院就诊,创伤指数(TI)≥17分,除外合并颅脑损伤及在急诊死亡的重症胸腹创伤患者为入选标准,干预组112例,对照组57例;干预组患者在就诊及入院时分别检查谷丙转氨酶(ALT)、谷草转氨酶(AST)、肿瘤坏死因子-α(TNF-α)、内毒素(LPS)、白细胞介素-6(IL-6)、磷脂酶A2(PLA2),对照组仅于入院时进行同样项目检查。结果干预组患者就诊时ALT为328.43±21.35U/L,AST为298.49±19.62U/L;入院时ALT为58.12±11.67U/L,AST为54.72±10.31U/L。对照组患者入院时ALT为350.88±27.72U/L,AST为302.91±24.31U/L;干预后ALT、AST降低,与干预前及对照组相比差异有统计学意义P<0.01。结论联合应用XBJ与NX治疗可显著减轻重症胸腹损伤后急性肝细胞功能损害,对减少并发症、预防多器官功能障碍综合征(MODS)有重要意义。
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| 关 键 词： | 重症胸腹损伤 急性肝细胞功能损害 血必净 钠洛酮 效果 |
Intervention Effect of Xuebijing Combined with Naloxone in Hepatic Cells Insufficiency during Severe Thoracoabdominal Injuries |
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| Li Zhiwei,Guo Yaqiong,Wang Wenjun.Intervention Effect of Xuebijing Combined with Naloxone in Hepatic Cells Insufficiency during Severe Thoracoabdominal Injuries[J].Journal of Medical Research,2015,44(2):156-158,116. |
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| Authors: | Li Zhiwei Guo Yaqiong Wang Wenjun |
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| Institution: | The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China;The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China;The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China;The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China;The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China;The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China;The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China;The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China;The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China;The Emergency Department of the 253th Hospital of PLA, Inner Mongolia 010051, China |
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| Abstract: | |
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| Keywords: | Severe thoraco abdominal injuries Acute hepatic cells insufficiency Xuebijing Naloxone Intervention effect |
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