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Loss of MIR15A and MIR16‐1 at 13q14 is associated with increased TP53 mRNA,de‐repression of BCL2 and adverse outcome in chronic lymphocytic leukaemia |
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| Authors: | Ke Lin Mosavar Farahani Yi Yang Gillian G. Johnson Melanie Oates Mark Atherton Angela Douglas Nagesh Kalakonda Andrew R. Pettitt |
| Affiliation: | 1. Department of Haematology, Royal Liverpool and Broadgreen University Hospitals NHS Trust, , Liverpool, UK;2. Department of Molecular and Clinical Cancer Medicine, University of Liverpool, , Liverpool, UK;3. Department of Haematology, Chong Qing Three Gorgers Centre Hospital, , Chong Qing, China;4. Cheshire and Merseyside Genetics Laboratories, Liverpool Women's Hospital, , Liverpool, UK |
| Abstract: | |
| Keywords: | CLL 13q14 MIR15A/16‐1 TP53 BCL2 |