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Bipolar polygenic loading and bipolar spectrum features in major depressive disorder
Authors:Anna Wiste  Elise B Robinson  Yuri Milaneschi  Sandra Meier  Stephan Ripke  Caitlin C Clements  Garrett M Fitzmaurice  Marcella Rietschel  Brenda W Penninx  Jordan W Smoller  Roy H Perlis
Affiliation:1. Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, , Boston, MA, USA;2. Center for Experimental Drugs and Diagnostics, Department of Psychiatry, , Boston, MA, USA;3. Analytical and Translational Genetics Unit, Massachusetts General Hospital, , Boston, MA, USA;4. Department of Psychiatry, VU University Medical Center, , Amsterdam, The Netherlands;5. Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, , Mannheim, Germany;6. Department of Biostatistics, Harvard School of Public Health, , Boston, MA, USA;7. Department of Psychiatry, Leiden University Medical Center, , Leiden;8. Department of Psychiatry, University Medical Center of Groningen, , Groningen, The Netherlands;9. Department of Psychiatry, Massachusetts General Hospital, , Boston, MA, USA
Abstract:
Keywords:bipolar disorder  depression  genetics  major depressive disorder  polygenic score  STAR*D
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