慢性心房颤动患者心房肌超声组织定征研究

目的探讨心房颤动(房颤)患者和窦性心律患者心房肌背向散射积分,诊断慢性房颤时心房肌病理性结构改变。方法选择风湿性瓣膜病患者46例,其中房颤组26例,窦性心律组20例。在左房后壁心肌和心包处测量背向散射积分值(IBS)及背向散射积分周期变异幅度(CVIB)。结果两组间年龄和性别构成比差异无统计学意义(P>0.05)。与窦性心律组比较,房颤组左房心肌标化IBS显著增大(P<0.05),而CVIB则显著降低(P<0.05)。结论慢性房颤患者心房肌显著纤维化和心房机械功能的下降是导致IBS值升高和CVIB降低的原因。

Ultrasonic tissue characterization study of atrial tissue in chronic atrial fibrillation

Objective To assess whether integrated backscatter(IBS) technique is feasible and sensitive in detecting and monitoring the histological characteristic of myocardium in atrial fibrillation. Methods Forty-six patients with rheumatic valvular disease (26 in chronic atrial fibrillation, and 20 in sinus rhythm) were enrolled. The post wall of left atrial and the correspondence pericardium were selected for detecting IBS and cyclic variation of IBS(CVIB). Results There was no significant difference in the age and sex ratio between two groups(P>~0.05 ). In patients with artrial fibrillation, IBS showed an increase,while CVIB showed a decrease compared with those in the patients with sinus rhythm. Conclusions The marked increase of IBS and decrease of CVIB was due to the obvious myocardium fibrosis and failed mechanical function.