氯胺酮减轻气管插管后咽喉痛的临床观察

目的观察氯胺酮喷喉是减轻术后咽喉痛的效果及安全性.方法 80例ASAⅠ～Ⅱ级择期全麻手术患者,随机分为氯胺酮喷喉组（K组）和对照组（C组）,每组40例.K组和C组分别于麻醉诱导后先喷氯胺酮0.2mg/kg（稀释至2mL）或生理盐水2mL,30s后行气管插管.观察气管导管拔除后1h、4h、8h、12h和24h的咽喉痛情况和严重程度.结果 K组病人咽喉痛的发生人数均比C组低,而且术后8h、12h和24h出现严重咽喉痛的病人也显著低于C组（P〈0.05）.结论氯胺酮喷喉可以显著降低术后咽喉痛的发生及严重程度,并且无明显副作用.

Clinical Observation of Ketamine for Attenuating Postoperative Sore Throat

Objective Postoperative sore throat is a common complication for the patients after tracheal intubation.this study was to evaluate whether ketamine can reduce postoperative sore throat by spraying throat.Methods Eighty,ASA Ⅰ～Ⅱ,patients undergoing elective surgery under general anaesthesia were randomly divided into ketamine group（K group） and control group（C group）,each 40 cases.K group and C group were the first spray after induction of anesthesia ketamine 0.2 mg/kg（diluted to 2 mL） or normal saline 2 mL,30 seconds before tracheal induction.Observe POST and severity of POST at 1,4,8,12 and 24 h after removal of endotracheal tube on a four-point scale（0～3）.Results POST occurred more frequently in Group C,when compared with Group K,and significantly more patients suffered severe POST in Group C at 4 and 24 h compared with Group K（P〈0.05）.Conclusion Ketamine spray jets can significantly reduce the incidence of POST and severity,and no obvious side effects.