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Pilot study in humans on the pharmacokinetics and safety of propofol 6% SAZN |
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| Authors: | Catherijne A.J. Knibbe Victorine S. Koster Leon P.H.J. Aarts Han J.M. Langemeijer Meindert Danhof |
| Affiliation: | Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands. |
| Abstract: | In a pilot study on the first application of Propofol 6% SAZN in humans, the pharmacokinetics and safety of the new product seem to be similar to those of Propofol 1% SAZN and Diprivan®  10 after bolus injection. The results will have to be confirmed in a larger clinical study in order to develop Propofol 6% SAZN as an alternative for Diprivan®10. |
| Keywords: | anaesthesia Clinical pharmacology Emulsion formulation Fat emulsion Propofol Pharmacokinetics |
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