单核细胞与高密度脂蛋白胆固醇比值和急性脑梗死患者颈动脉狭窄的关系

目的 探讨单核细胞与高密度脂蛋白胆固醇比值(MHR)和急性脑梗死(ACI)患者颈动脉狭窄(CAS)的关系.方法 选取242例ACI患者为研究对象,将41例无CAS的ACI患者设为对照组,201例有CAS的患者设为狭窄组.根据超声诊断结果将狭窄组分为轻度狭窄组(n=88)、中度狭窄组(n=61)、重度及闭塞组(n =52...

Correlation between monocyte to high-density lipoprotein cholesterol ratio and carotid artery stenosis in patients with acute cerebral infarction

Objective To explore the relationship between monocyte to high-density lipoprotein cholesterol ratio(MHR)and carotid artery stenosis(CAS)in patients with acute cerebral infarction(ACI).Methods A total of 242 ACI patients were selected as study objects,among whom 41 cases without CAS were selected as control group and 201 patients with CAS were selected as stenosis group.According to the ultrasonic results,the stenosis group was furtheRdivided into mild stenosis group(n=88),moderate stenosis group(n=61),severe stenosis and occlusion group(n=52).Logistic regression analysis was used to determine the risk factors of CAS in ACI patients,and ROC curve was used to assess the predictive value of MHRin ACI patients with CAS.Results The MHRof the stenosis group was significantly higheRthan that of the control group(P<0.05).The MHRvalues of the moderate stenosis group,severe stenosis and occlusion group were significantly higheRthan those of the control group(P<0.05).Logistic regression analysis showed that MHRwas an independent risk factoRfoRCAS in ACI patients.ReceiveRoperating characteristic(ROC)curve results suggested that when the MHRvalue was 0.535,the maximum predictive value of CAS foRACI patients was the highest,sensitivity was 40.30%,and specificity was 85.40%(P<0.05).Conclusion MHRis an independent risk factor,and may be an indicatoRto predict CAS in ACI patients.