血浆中性粒细胞与淋巴细胞比值预测急性缺血性脑卒中机械取栓患者半年预后的价值

目的 探讨血浆中性粒细胞与淋巴细胞比值(NLR)预测急性缺血性脑卒中(AIS)机械取栓患者半年预后的价值.方法 将105例AIS机械取栓患者根据半年后改良Rankin量表(mRS)评分结果分为预后良好组48例和预后不良组57例,比较2组患者的临床资料.将有统计学差异的相关指标采用二元Logistic回归分析,采用受试者...

Value of plasma neutrophil to lymphocyte ratio in predicting prognosis after half a year in acute ischemic stroke patients with mechanical thrombectomy

Objective To explore the value of plasma neutrophil to lymphocyte ratio(NLR)in predicting prognosis after half a year in acute ischemic stroke(AIS)patients with mechanical thrombectomy.Methods Totally 105 AIS patients with mechanical thrombectomy were divided into good prognosis group(n=48)and poor prognosis group(n=57)according to the score of modified Rankin Scale(mRS)after half a year,and the clinical materials were compared between the two groups.Binary Logistic regression analysis was used to analyze the related indicators with statistical differences,and the receiver operating characteristic(ROC)curve was used to evaluate the predictive value.Results There were significant differences in operation time,neutrophil percentage,lymphocyte percentage and NLR between the two groups(P<0.05).There were significant differences in operation time and National Institute of Health Stroke Scale(NIHSS)between anterior circulation infarction group and posterior circulation infarction group(P<0.05).There was no significant difference in clinical materials between internal carotid artery occlusion group and middle cerebral artery occlusion group(P>0.05).Binary Logistic regression analysis showed that operation time and NLR were independent risk factors for predicting prognosis after half a year in acute cerebral infarction patients with mechanical thrombectomy.The area under the ROC curve(AUC)of NLR in predicting prognosis after half a year in acute cerebral infarction patients with mechanical thrombectomy was 0.759.When the optimal critical value was 4.685,the Youden index was 0.565,the sensitivity was 74.50%,the specificity was 82.00%,and the 95%CI was from 0.662 to 0.855.The AUC of operation time in predicting prognosis after half a year in acute cerebral infarction patients with mechanical thrombectomy was 0.623.When the optimal cut-off value was 81.500 min,the Youden index was 0.245,the sensitivity was 74.50%,the specificity was 50.00%,and the 95%CI was from 0.516 to 0.731.Conclusion The increase of plasma NLR has a good predictive value for the poor prognosis after half a year in AIS patients with mechanical thrombectomy.