慢性阻塞性肺疾病合并肌少症研究进展

慢性阻塞性肺疾病(COPD)是一种复杂的、具有高度异质性的全身性疾病.肌少症作为COPD多种合并症中之一,能够加速疾病进程,增加致残率和全因死亡率.近年来研究发现,COPD合并肌少症的危险因素为活动受限、营养不良、脂肪沉积等.结合肺功能相关指标与肌肉测量技术能够较精确的预测住院患者生存率和死亡率,在此基础上进行个性化干...

Progress of chronic obstructive pulmonary disease complicated with sarcopenia

Chronic obstructive pulmonary disease(COPD)is a complex and highly heterogeneous systemic disease.As one of the multiple complications of COPD,sarcopenia can accelerate the disease process,increase the disability rate and all-cause mortality.In recent years,studies have founded that the risk factors of COPD with sarcopenia were limited activity,malnutrition,fat deposition and so on.Combined with pulmonary function related indicators and muscle measurement techniques,the survival and mortality rates of hospitalized patients can be predicted more accurately.On this basis,individualized intervention is of great clinical significance to improve the outcome and prognosis of the disease.This article reviewed the risk factors,diagnosis,intervention and treatment of COPD and sarcopenia.