桑夏苓术汤治疗脑卒中相关性肺炎的效果

目的 探讨桑夏苓术汤对脑卒中相关性肺炎(SAP)患者血清炎症因子和外周血淋巴细胞亚群的影响.方法 将110例SAP患者根据随机数字表法分为2组,对照组55例实施常规治疗,观察组55例在对照组基础上服用桑夏苓术汤.治疗前后检测血清炎症因子、外周血淋巴细胞亚群水平,比较2组疾病改善情况及临床疗效.结果 2组治疗后C反应蛋白...

Effect of Sangxia Lingzhu Decoction in treating patients with stroke associated pneumonia

Objective To investigate effect of Sangxia Lingzhu Decoction on serum inflammatory factors and peripheral blood lymphocyte subsets in patients with stroke associated pneumonia(SAP).Methods A total of 110 patients with SAP were selected,and were divided into two groups by random number table method.A total of 55 patients receiving routine treatment were selected as control group,and the rest of 55 patients given Sangxia Lingzhu Decoction based on the control group were selected as observation group.Levels of serum inflammatory factors and peripheral blood lymphocyte subsets were detected before and after treatment.Disease improvement conditions and clinical effects of two groups were compared between two groups.Results The levels of C-reactive protein,interleukin(IL)-1β,IL-4,IL-6 and TNF-αin the two groups after treatment were significantly lower than those before treatment,and the levels of CD3⁺,CD4⁺,CD8⁺and CD4⁺/CD8⁺in two groups after treatment were significantly higher than those before treatment(P<0.05).After treatment,the levels of C-reactive protein,IL-1β,IL-4,IL-6 and TNF-αin the observation group were significantly lower,the levels of CD3⁺,CD4⁺,CD8⁺and CD4⁺/CD8⁺in the observation group were significantly higher,and disappearance time of cough,fever,lung dampness rale as well as suffocation in the observation group was significantly shorter than that in the control group(P<0.05).Total effective rate in observation group was significantly higher than that in the control group(P<0.05).Conclusion Sangxia Lingzhu Decoction can relieve inflammatory reactions in patients with stroke associated pneumonia,regulate the levels of peripheral blood lymphocyte subsets,shorten disease improvement time and improve clinical effect.