颅内动脉狭窄的血管内支架治疗

目的评价症状性颅内动脉狭窄血管内支架置入治疗的疗效、安全性和操作技术。方法17例局限性颅内血管狭窄患者出现与血管狭窄有关的神经功能障碍,内科抗凝、抗血小板治疗无效。采用经皮支架辅助血管成形术,使狭窄血管扩张。术后3个月进行经颅彩色多普勒检查和(或)数字减影血管造影检查及临床症状随访。结果17例患者血管内支架均成功置人,血管狭窄率从术前的平均83％降至术后的5％。均无与手术相关的颅内出血发生。短期内(3个月)随访未见再狭窄,没有短暂性脑缺血发作或脑卒中发生,临床症状改善。结论经皮血管内支架置入术是治疗症状性颅内动脉狭窄安全、有效的手段。

Endovascular stenting for intracranial arterial stenosis

Objective To evaluate the safety, efficacy and technology in the treatment of symptomatic intracranial arterial stenosis. Methods Seventeen intracranial stenotic arteries in 17 consecutive patients with neurological symptoms irresponsible to anti-platelet and anticoagulation therapy, were undertaken specially designed endovascular dilation stenting. Three months after the procedure, transcranial Doppler(TCD) and/or digital subtraction angiography(DSA) was performed with follow-up clinically. Results All patients experienced symptom relief after stent-assisted angioplasty. Angiography demonstrated good patency of stented lesions in all patients with stenotic degree reducing from 83% to 5% and none sufferring from procedural-related intracranial hemorrage. Three months follow-up for all cases exhibited good patency of stented lesions with no transient ischemic attacks(TIAs) or strokes and having clinical symptom improved. Conclusion Stent-assisted angioplasty can provide a favorable outcome with good patency for intracranial arterial stenosis.