高频电波刀行电圈切除治疗宫颈病变的临床应用探讨

目的　评价高频电波刀行电圈切除 (LEEP)治疗宫颈病变中的临床应用价值。方法　回顾性分析我院 2 71例LEEP治疗宫颈病变的临床资料 ,所有病例均行阴道镜下多点活检和LEEP术后病理诊断 ,在炎症和赘生物病变外缘 3mm进出电极 ,对于CINI与HPV感染患者 ,电极在病变边缘外 5mm进出。结果　阴道镜下多点活检与LEEP术标本的病理诊断差别有显著性 (P <0 0 5 )。 2 71例患者术后随访 2 4 3例 ,术后复查宫颈细胞学 ,仅 9 0 5 %出现细胞核肥大和核异质。结论　LEEP对包括炎症、损伤、癌前病变、HPV感染等宫颈病变是一种非常理想的诊断、治疗手段。宫颈细胞学检查、阴道镜下多点活检、LEEP术后病理诊断构成了宫颈病变系统的诊断模式。LEEP可以广泛地应用于治疗CIN各级病变 (原位癌除外 ) ,LEEP也适用于CINI的治疗 ,LEEP治疗的范围可以在病变边缘外 5mm处进出电极

Evaluation of loop electrosurgical excision procedure in the treatment of cervical diseases

Objective To evaluate loop electrosurgical excision procedure (LEEP) in the treatment of cervical diseases Methods Two hundred and seventy-one patients with cervical diseases underwent LEEP in clinic of Fujian Province Maternal & Child Hospital from 2000 to 2002 were analyzed retrospectively All the patients were treated by excision of 3 mm or 5 mm outside from the outskirts of the cervical lesions following colposcopy and biopsy Results Histological diagnosis were discrepancy between biopsies directed by colposcope and LEEP specimens( P <0 05) After LEEP treatment,243 women were followed up and 9 05 % of them showed cervical cytological abnormal Conclusions LEEP is an ideal method of cervical diseases diagnosis and treatment,especially in the treatment of CIN I to CIN III It can provide intact sample for pathological diagnosis,and 5 mm outside from the edge of the lesion is suitable for treatment