肝转移出现的时段对非小细胞肺癌预后的影响

目的：探讨肝脏转移出现的时段对非小细胞肺癌患者生存的影响。方法：选择1999-01/2006-09在我院死亡的非小细胞肺癌238例,回顾分析肝转移出现时间对预后的影响。结果：肺癌患者初诊时出现肝转移20例,中位生存期7（5,9）个月;初次诊断无肝转移253例,中位生存期13（12,14）个月,差异显著（P=0.008 5）。而总患病期间出现肝转移以及首发肝转移对预后影响不显著。结论：初诊时出现肝脏转移是非小细胞肺癌患者显著影响预后的因素。

Effect of Hepatic Metastasis Appearing Time on Prognosis of Non Small Cell Lung Cancer Patients

Objective： To discuss the effect of hepatic metastasis appearing time on survival of patients with non small cell lung cancer.Methods：Two hundred thirty eight patients with non small cell lung cancer were chosen,who died in our hospital from Jan.1999 to Sep.2006.We reviewed the effect of hepatic metastasis time on prognosis.Results：There were 20 patients with hepatic metastasis at initial diagnosis,median survival time was 7（5,9）months;those patients without hepatic metastasis at initial diagnosis 253 cases,median 13（12,14）months.There was a significant difference（P=0.008 5）.Hepatic metastasis appearing during the whole life or as the first metastasis site was not a significant prognosis factor.Conclusion：Hepatic metastasis at initial diagnosis is a significantly poor prognosis factor for patients with non-small cell lung cancer.