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| 网织红细胞膜生物物理特性的研究 | |
| 引用本文： | 谢利德,杨海杰,孙大公,文宗曜,谭文长. 网织红细胞膜生物物理特性的研究[J]. 生物医学工程学杂志, 2006, 23(2): 392-395 |
| 作者姓名： | 谢利德 杨海杰 孙大公 文宗曜 谭文长 |
| 作者单位： | 1. 承德医学院,生物医学工程系,承德,067000;北京大学,基础医学院,物理教研室,北京,100083;北京大学,力学与工程科学系,北京,100871 2. 承德体育运动学校,承德,067000 3. 北京大学,基础医学院,物理教研室,北京,100083 4. 北京大学,力学与工程科学系,北京,100871 |
| 基金项目： | 中国科学院资助项目;中国博士后科学基金;河北省博士科研项目 |
| 摘 要： | 用苯肼使动物造成急性溶血性贫血的方法，诱发动物体内新生网织红细胞大量增多，通过对新生网织红细胞的电泳率、渗透脆性、膜的流动性等生物物理指标连续72h的测量，发现网织红细胞在由网织红细胞转变为成熟红细胞的过程中．其生物物理特性有明显改变。这对研究由于贫血等原因造成的网织红细胞增多情况下，全血的微观流变学特性具有重要的临床意义，同时对新生网织红细胞膜的生物物理特性加以系统研究，具有重要的基础理论研究价值。 |
| 关 键 词： | 网织红细胞 电泳率 生物物理特性 渗透脆性 膜的流动性 |
| 收稿时间： | 2003-11-28 |
| 修稿时间： | 2003-11-282004-03-15 |
On the Biophysics Characteristics of Reticulocytes |
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| Xie Lide,Yang Haijie,Sun Dagong,Wen Zongyao,Tan Wunchang. On the Biophysics Characteristics of Reticulocytes[J]. Journal of biomedical engineering, 2006, 23(2): 392-395 | |
| Authors: | Xie Lide Yang Haijie Sun Dagong Wen Zongyao Tan Wunchang |
| Affiliation: | 1. Department of Biomedical Engineering, Chengde Medical College, Chengde 067000,China; 2 Department of Medical Physics, Medical College of Peking University, Beijing 100083,China; 3 Department of Mechanics and Engineering Science, Peking University, Beijing 100871 ,China; 4.School of Physical Education of Chengde,Chengde 067000,China |
| Abstract: | This paper reports an in vivo study on the biophysics characteristics of reticulocytes. Anemia was induced by injection of phenylhydrazine in rabbits. The measurements, including electrophoresis rate, hematolytic rate, fluorescent polarization and the changing anisotropic value, were performed in vivo for 72 hours in the process of reticulocytes growing into erythrocytes. It was shown that there were obvious changes in the biophysics characteristics of reticulocytes in this course. Therefore, the findings are of signifiicance to basic, theoretical and clinical studies. |
| Keywords: | Reticulocyte Electrophoretic mobility Biophysics characteristics Osmotic Fluorescent polarization |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |