| 头颈部鳞癌干细胞标志物的研究进展 |
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| 引用本文： | 佟冬冬,张风河,姚瑶,张兆弢.头颈部鳞癌干细胞标志物的研究进展[J].生物医学工程研究,2011,30(4):260-264. |
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| 作者姓名： | 佟冬冬 张风河 姚瑶 张兆弢 |
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| 作者单位： | 山东大学口腔医学院口腔颌面外科,山东省口腔生物医学重点实验室,济南250012 |
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| 基金项目： | 山东省科学技术发展计划项目 |
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| 摘 要： | 肿瘤干细胞(CSC)是一群具有自我更新能力和多向分化潜能的肿瘤细胞,虽然CSC在肿瘤细胞总数中只占很小比例,但在肿瘤的起源、发展、转移及复发等方面均有重要的作用.过去几年内研究者已经证明包括头颈部鳞癌干细胞在内的许多CSCs的存在,并分别针对头颈部肿瘤干细胞与头颈部鳞癌的关系、肿瘤干细胞的生物学特性和鉴定标志等问题展开...
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| 关 键 词： | 肿瘤 头颈部鳞癌 肿瘤干细胞 干细胞标志物 肿瘤标记 表面标记 生物学 |
Advances in Head and Neck Cancer Stem Cell Markers Research |
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| TONG Dongdong
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ZHANG Fenghe
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YAO Yao
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ZHANG Zhaotao.Advances in Head and Neck Cancer Stem Cell Markers Research[J].Journal Of Blomedical Englneerlng Research,2011,30(4):260-264. |
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| Authors: | TONG Dongdong ZHANG Fenghe YAO Yao ZHANG Zhaotao |
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| Institution: | tao(Department of Oral and Maxillofacial Surgery,Stomatology School of Shandong University,Jinan 250012,China) |
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| Abstract: | Cancer stem cells(CSCs)are a group of tumor cells with stem cell-like properties such as infinite self-renewal and multi—differentiation potential.Although rare,CSCs play important roles in tumor initiation,progression,recurrence and metastasis.Recent studies show that multiple CSCs are present,including head and neck squamous cell carcinomas.This article reviews the association of head and neck cancer stem cells with head and neck squamous cell carcinomas,biological characteristic of head and neck cancer stem cells,and identification marker.in the sense of research progress in CSCs and head and neck cancer stem cells marker. |
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| Keywords: | Tumor Head and neck squamous cell carcinomas Cancer Stem cells:Cancer stem cells markers Tumor markers Surface markers Biology |
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