Two new saponins from the leaves of Panax notoginseng |
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| Authors: | Ji-Wu Huang Fang-You Chen Chuang-Jun Li Jing-Zhi Yang Jie Ma Xiao-Guang Chen |
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| Affiliation: | State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China |
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| Abstract: | ![]()
Two new saponins, notoginsenosides Ng1 (1) and Ng2 (2), together with seven known compounds (3–9), were isolated from the leaves of Panax notoginseng. Their structures were elucidated by UV, IR, HRESIMS, and NMR experiments. Compounds 6 and 7 showed moderate cytotoxic activities against HCT-116, with IC50 values of 4.98 and 0.64 μmol/L, respectively. |
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| Keywords: | Araliaceae Panax notoginseng saponins anticancer |
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