血液灌流联合血液透析救治急性药物中毒的临床研究

目的 探讨分析血液灌流联合血液透析救治急性药物中毒的临床疗效.方法 回顾性分析我院2007年3月至2010年12月收治的120例急性药物中毒患者,将其随机分为两组,60例接受常规综合治疗,60例在接受常规综合治疗的基础上行血液灌流联合血液透析(HDP).观察比较两组平均住院时间、病死率等情况.结果 实验组平均住院时间为(8.1±3.7)d,昏迷时间为(7.3±3.5)h,病死率为5.0％;对照组平均住院时间为(15.6±5.0)d,昏迷时间为(17.1±1.2)h,病死率为11.7％.结论 血液灌流联合血液透析配合常规的综合治疗应用于急性药物中毒临床疗效较好,值得在临床上推广.

Clinical study on hemoperfusion combined with hemodialysis in treatment for acute drug poisoning

ObJective To investigate the clinical efficacy of hemoperfusion combined with hemodialysis （HDP） in treatment for acute drug poisoning. Methods 120 cases of acute drug poisoning patients were randomly divided into experiment and control groups, 60 cases of each group. The control group received conventional treatment, while the experiment group received HDP based on the conventional treatment. We compared the clinical efficacy in the two groups. Results In the experimental group, the average length of stay and duration of coma were shorter than those of the control group and mortality was lower than that of the control group, the differences were statistically significant （P〈0.05）. Conclu- sion HDP with conventional treatment can provide better clinical efficacy in acute drug poisoning treatment, which is worthy in clinical promotion.