湖南省人群戊型肝炎病毒感染状况初步分析

目的 了解湖南省一般人群中戊型肝炎病毒感染状况，为湖南省戊肝防制提供基本的依据。方法 采用酶联免疫法检测一般人群血清标本抗-HEV IgM和IgG抗体。结果 8个县（市、区）1，553名一般人群血清抗-HEVIgM和IgG抗体平均阳性率分别为0．32％、21．70％，8个县（市、区）一般人群抗-HEVIgG抗体阳性率差异较大，从最低为0至最高达70.73％；无论是全部8个县（市、区）还是4个抗-HEW1只G抗体阳性率高的县（市、区），一般人群中男、女性抗-HEVIgG抗体阳性率差异无显著性，且随着年龄的上升而上升。结论 湖南省部分地区可能曾发生过戊肝爆发，但由于戊肝疫情监测的敏感性较低而未能及时发现。今后应加强对戊肝的监测和科学研究力度，掌握戊肝疫情变化动态和流行病学特征，降低戊肝发病率。

Analysis of infection status of HBE in population of Hunan Province

Objective To understand the infectious status of hepatitis E virus(HEV) in general population of Hunan Province and provide a scientific basis for controlling the disease. Methods IgM and IgG Antibodies against HEV were detected with enzyme-linked immenosorbent assays(ELISA). Results The average positive rates of IgM and IgG against HEV were 0.32% and 21.70% in 1,553 persons in 8 counties(cities,districts).The average positive rates of IgG varied greatly in 8 counties(cities,districts),from 0 up to 70.73%;There were no significant differences between male and female in IgG positive rates,and the IgG positive rates were increased along with the increase of age. Conclusion The outbreak of hepatitis E might have occurred in some areas without being detected due to lower sensitiveness of monitoring,detection and capability.Thus in-depth study and monitoring of hepatitis E be strengthened in the future in order to reduce incidence of hepatitis E.