生活事件对试管婴儿辅助助孕临床妊娠率的影响

目的 探讨生活事件对试管婴儿辅助助孕临床妊娠率的影响。方法 收集接受试管婴儿治疗不孕患者的一般情况、内膜厚度、内膜形态等生理因素以及生活事件,并追踪记录其临床妊娠结局。采用多因素Logistic回归,分析生活事件对妊娠结局的影响。结果 生活事件、内膜形态、内膜厚度、移植优质胚胎比例是妊娠率的重要影响因素。主观生活事件(SE)增加1分,成功妊娠的几率为原来的0.895;客观生活事件(OE)中第2类应激强度(OE2)增加1分,成功妊娠的几率为原来的0.894。结论 不孕患者经历的生活事件过多,应激水平过高,不利于妊娠。

Effect of life events on the clinical pregnancy rate in in vitro fertilization-embryo transfer women

Objective To investigate the effect of life events on the clinical pregnancy rate of in vitro fertilization-embryo transfer (IVF-ET) women.Methods The basic information,the physiological factors such as the thickness and the shape of endometrium and life events were collected.Then the pregnancy outcomes were recorded.The data were analyzed by multiple factors logistic regression analysis.Results Endometrial morphology,endometrial thickness,the ratio of high-quality embryos transferred and life events were important factors for the clinical pregnancy rate.1-point increase in subjective life events (SE) can lead the clinical pregnancy rate to decrease to about 0.895 of the original.With 1-point increase in the second objective life events (OE2),the probability of a successful pregnancy would reduce to 0.894 of the original.Conclusion More life events and high stress level are negative factors that are not conducive to pregnancy.