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子宫内膜微刺激与宫腔内人工授精患者妊娠结局的新研究
引用本文:郑嘉华,张丹,王炳雷,周寒,王玮. 子宫内膜微刺激与宫腔内人工授精患者妊娠结局的新研究[J]. 生殖与避孕, 2017, 0(8): 685-688. DOI: 10.3760/cma.j.issn.2096-2916.2017.08.017
作者姓名:郑嘉华  张丹  王炳雷  周寒  王玮
作者单位:1. 河北医科大学第二医院生殖科,石家庄,050000;2. 河北医科大学第二医院神经内科,石家庄,050000
摘    要:
卵巢刺激与宫腔内人工授精(IUI)是世界范围内治疗不孕患者经常用到的基本助孕方案,但其临床妊娠率相对较低;相关文献表明内膜微刺激通过提高内膜容受性能改善不明原因反复移植失败患者体外受精-胚胎移植(IVF-ET)的妊娠结局,那么,其是否同样有益于改善IUI的妊娠结局呢?本文就有关内膜微刺激改善子宫内膜容受性的最新作用机制及IUI临床妊娠率能否得到改善的最新研究进行概述。

关 键 词:内膜微刺激  宫腔内人工授精(IUI)  子宫内膜容受性  临床妊娠率

Influence of endometrial mechanical stimulation on clinical pregnancy rate of intrauterine insemination
Zheng Jiahua,Zhang Dan,Wang Binglei,Zhou Han,Wang Wei. Influence of endometrial mechanical stimulation on clinical pregnancy rate of intrauterine insemination[J]. Reproduction and Contraception, 2017, 0(8): 685-688. DOI: 10.3760/cma.j.issn.2096-2916.2017.08.017
Authors:Zheng Jiahua  Zhang Dan  Wang Binglei  Zhou Han  Wang Wei
Abstract:
The first line of fertility treatment frequently applied m the world is intrauterine insemination (IUI) with ovarian stimulation.The effectiveness of this procedure is,however,still low.There is evidence of significant difference on the clinical pregnancy rate when endometrial scratching performed prior to embryo transfer in women undergoing in vitro fertilization-embryo transfer (IVF-ET),who stand with repeated transfer failure.Is it also beneficial to IUI? Here,we present an overview about the up to date mechanism and the role of endometrial injury in the cycle preceding ovarian stimulation for IUI cycle on the clinical pregnancy rate.
Keywords:Endometrial scrach  Endometrial local injury  Intrauterine insemination (IUI)  Endometrial receptivity  Clinical pregnancy rate
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