Effects of polyphenol compounds fromAlchemilla vulgaris on morphofunctional state of thyroid gland in rats exposed to low temperature |
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| Authors: | Yu. I. Borodin V. G. Selyatitskaya L. A. Obukhova N. A. Pal'chikova S. V. Odintsov T. A. Kukushkina |
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| Affiliation: | (1) Institute of Clinical and Experimental Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk;(2) Institute of General Pathology and Human Ecology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk;(3) Central Siberian Botanic Garden, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk |
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| Abstract: | In control rats and animals receiving polyphenol compounds extracted fromAlchemilla vulgaris, intense cooling stimulated synthesis of thyroid hormones and promoted their peripheral deiodination. In control rats, the period of recovery after cooling (readaptation period) was characterized by a compensatory reduction in thyroid function. In rats receiving test preparation, this period was characterized by significant activation of thyroid hormone synthesis and by further growth of reserve follicles that appeared during the cooling. Translated fromByulleten' Eksperimental'noi Biologii i Meditsyni, Vol. 127, No. 6, pp 697–699, June, 1999 |
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| Keywords: | polyphenol compounds thyroid gland morphometry thyroid hormones cooling |
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