| 骨髓干细胞动员剂对大鼠急性心肌梗死肌钙蛋白Ⅰ的影响 |
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| 引用本文： | 郭素萍,高传玉,刘煜昊.骨髓干细胞动员剂对大鼠急性心肌梗死肌钙蛋白Ⅰ的影响[J].实用诊断与治疗杂志,2005,19(2):114-114,116. |
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| 作者姓名： | 郭素萍 高传玉 刘煜昊 |
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| 作者单位： | 河南省人民医院心内科,郑州市,450003 |
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| 摘 要： | 目的:探讨粒细胞集落刺激因子动员骨髓干细胞,对大鼠急性心肌梗死肌钙蛋白I的影响。方法:把20只大 鼠随机分为两组:对照组及试验组,每只大鼠均于24 h,7 d采血,测定心肌肌钙蛋白I的水平。结果:实验组心肌肌钙蛋白 I在24 h,7 d较对照组均显著下降(P<0.05),有统计学意义。结论:粒细胞集落刺激因子通过动员骨髓干细胞,迁移到 心肌,修复受损的心肌,减少心肌肌钙蛋白I的释放。
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| 关 键 词： | 骨髓干细胞动员剂 大鼠 急性心肌梗死 肌钙蛋白Ⅰ |
| 文章编号： | 1672-3457(2005)02-114-02 |
Influence of mobilizated bone marrow stem cells on cardiac troponin-Ⅰ of acute myocardial infarction rats |
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| GUO Suping,GAO Chuanyu,LIU Yuhao.Influence of mobilizated bone marrow stem cells on cardiac troponin-Ⅰ of acute myocardial infarction rats[J].Journal of Practical Diagnosis and Therapy,2005,19(2):114-114,116. |
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| Authors: | GUO Suping GAO Chuanyu LIU Yuhao |
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| Institution: | GUO Suping,GAO Chuanyu,LIU Yuhao. Department of Cardiology,Henan Provincial People's Hospital,Zhengzhou 450003,China |
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| Abstract: | Objective To explore the effect of bone marrow stem cells mobilization on cardiac troponin-I in acute myocardial infartion rats. Methods Twenty rats were randomly divided into 2 groups. cTnI levels were measured in 24 hours and 7 days respectively. Results cTnI levels was decreased in 24 hours and 7 days in the experiment group (P<0. 05). There was a significant difference between the experiment group and control group. Conclusion G-CSF may decrease cTnI levels by mobilizated bone marrow stem cells and respairing injured myocardium. |
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| Keywords: | Myocardial infarction bone marrow stem cells mobilization cardiac troponin-I |
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