弓形虫感染家庭聚集性研究

目的 探讨弓形虫感染的家庭聚集性。方法 对487户临床病例家属计1436人的血清用间接血凝试验(IHA)及酶联免疫吸附试验(ELISA)作弓形虫感染检测并作小鼠实验。数据采用二项分布齐性检验的G统计学方法分析。结果 弓形虫抗体阳性237户，占总户数的48．7％，阳性342人，占总检查人数的23．8％。30只小白鼠唾液涂片中1只发现弓形虫滋养体；10例弓形虫病人唾液涂片中1例查见典型的弓形虫滋养体2只。结论 弓形虫感染有明显的家庭聚集性。

STUDY ON FAMILY CLUSTERING OF TOXOPLASMA INFECTIONS

Objective To investigate the family clustering of Toxoplasma infections. Methods The enzyme-linked immunosorbent assay (ELISA) and indirect hemagglutination test (IHA) were performed to detect antibodies to To.xoplasma in sera of 1 436 people from 487 families with clinical cases. The data were analysed with G test of homogeneous in statistical binomial distribution. Results Three hundred and forty-two people of 237 families showed sera positive, with rates of 48.7% of family and 23.8% of population. A saliva trophozoite in one of 30 rats was found and so were two typical saliva parasites in one of 10 cases, Conclusion There is a significant evidence of family clustering of Toxoplasma infections (T=6.48,P<0.01).