常规超声和超声造影在肝脏良恶性局灶性病变鉴别诊断中的价值对比

目的探讨常规超声和超声造影在肝脏良恶性局灶性病变鉴别诊断中的价值对比。方法回顾性分析常规超声和超声造影检查的230例肝脏良恶性局灶性病变患者共246个病灶的临床资料,比较两种检查方法鉴别诊断肝脏良恶性局灶性病变的效能。结果在246个病灶中,常规超声诊断得出肝脏局灶性病变良性结果53个,肝脏局灶性病变恶性结果136个,共准确诊断189个;超声造影诊断得出肝脏局灶性病变良性结果88个,肝脏局灶性病变恶性结果144个,共准确诊断232个。常规超声和超声造影对肝脏局灶性病变良恶性诊断的敏感度(91.3%,96.6%)、特异度(54.6%,90.7%)、阳性预测值(75.6%,94.1%)、阴性预测值(80.3%,94.6%)及准确性(76.8%,94.3%),除敏感性外,其余指标差异均有统计学意义(均P0.05)。结论在肝脏良恶性局灶性病变鉴别诊断中,超声造影的出现和发展为肝脏良恶性局灶性病变的鉴别诊断提供了新的途径,与常规超声鉴别诊断相比较,具有更高的诊断效能。

Comparison of differential diagnostic value between conventional ultrasound and ultrasonic contrast in diagnosing benign and malignant focal liver lesions

Objective To investigate the value of conventional ultrasound and ultrasonic contrast in the differential diagnosis of benign and malignant focal liver lesions (FLL).Methods A total of 230 patients diagnosed of benign or malignant FLL by conventional ultrasound and ultrasonic contrast in our hospital were enrolled,whose clinical data and liver pathology were retrospectively analyzed.Results Among 230 patients with 246 FLL,there were 53 cases of benign FLL and 136 of malignant diagnosed by conventional ultrasound (totally 189/246),and 88 of benign and 144 of malignant by ultrasound contrast (totally 232/246 ).Sensitivity,specificity,positive predictive value,negative predictive value and accuracy of conventional ultrasonography and contrast-enhanced ultrasound in differential diagnosis of benign and malignant FLL were 91 .3% vs.96.6%,54.6% vs.90.7%,75.6% vs.94.1 %,80.3% vs.94.6% and 76.8% vs.94.3%, respectively.All indicators except sensitivity were statistically significant different (all P <0.05 ).Conclusion Compared with conventional ultrasound,ultrasonic contrast was more effective in differential diagnosis of benign and malignant FLL.