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| 经颅多普勒频谱参数与急性颅脑损伤患者颅内压的关系 | |
| 引用本文： | 陈兵,莫大鹏,李臻琰,刘尚明,刘运生.经颅多普勒频谱参数与急性颅脑损伤患者颅内压的关系[J].中华神经医学杂志,2004,3(3):201-203. |
| 作者姓名： | 陈兵 莫大鹏 李臻琰 刘尚明 刘运生 |
| 作者单位： | 1. 广东医学院附属医院神经外科,广东,湛江,524001 2. 首都医科大学宣武医院神经外科,北京,100053 3. 中南大学湘雅医院神经外科,湖南,长沙,410008 |
| 摘 要： | 目的探讨急性颅脑损伤患者的经颅多普勒频谱参数与颅内压的关系。方法应用TCD检测20例急性中、重型颅脑损伤患者双侧大脑中动脉,同时行颅内压监测。结果经颅多普勒频谱参数cf、PI、af、RI、ae均和ICP正相关,Vd、ac和ICP负相关,其中cf与ICP的相关系数最大。建立TCD相关参数与ICP的多元线性回归方程:ICP=0.312MAP-1.531Vd+21.437PI-15.059ac+38.722cf(P<0.001,R2=0.920估计值的标准差=4.0972mmHg)。结论经颅多谱勒频谱参数可以反应颅脑损伤患者的颅内压的改变。综合研究经颅多谱勒频谱参数、血压与颅内压的关系是应用经颅多普勒无创监测颅内压的方向。 |
| 关 键 词： | 经颅多普勒频谱参数 急性颅脑损伤 颅内压 TCD 脑血液流变学 |
| 文章编号： | 1671-8925(2004)03-0201-003 |
| 修稿时间： | 2003年6月9日 |
Relations between parameters of transcranial Doppler ultrasonography and intracranial pressure in patients with acute craniocerebral injury |
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| CHEN Bing,MO Dapeng,LI Zhenyan,LIU Shangming,LIU Yunsheng.Relations between parameters of transcranial Doppler ultrasonography and intracranial pressure in patients with acute craniocerebral injury[J].Chinese Journal of Neuromedicine,2004,3(3):201-203. | |
| Authors: | CHEN Bing MO Dapeng LI Zhenyan LIU Shangming LIU Yunsheng |
| Institution: | CHEN Bing1,MO Dapeng2,LI Zhenyan3,LIU Shangming3,LIU Yunsheng31Department of Neurosurgery,Affiliated Hospital of Guangdong Medical College,Zhanjiang 524001,China, 2Department of Neurosurgery,Xuanwu Hospital,Capital University of Medical Sciences,Beijing 100053,China, 3Department of Neurosurgery,Xiangya Hospital,Central South University,Changsha 410008,China |
| Abstract: | Objective To study the relations between parameters of transcranial Doppler (TCD) ultrasonography and intracranial pressure (ICP) in acute craniocerebral injury patients. Methods TCD ultrasonograms of bilateral middle cerebral arteries and ICP were monitored in 20 acute patients with moderate and severe craniocerebral injury. Results The relationships between ICP with the parameters of TCD like cf, PI, af, RI and ae were positively correlated, while ones with Vd, ac were negatively correlated. The correlation coefficient of ICP with cf was the most prominent. A multiple linear regression equation on the relationship between TCD parameters and ICP was established as: ICP=0.312MAP-1.531Vd+21.437PI-15.059ac+38.722cf (P<0.001, R2=0.920, standard deviation of estimated value =4.0972 mmHg). Conclusion These parameters of TCD correlate with ICP significantly in acute cranialocerebral injury patients. It is promising to monitor the ICP noninvasively by studying the comprehensive relations between ICP and TCD parameters, bood pressure. |
| Keywords: | transcranial Doppler ultrasonography intracranial pressure craniocerebral injury |
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