正常高值血压者血管结构的变化

目的利用无创方法探讨正常高值血压者血管结构的改变。方法试验分正常高值组（90例）及正常对照组（60例）。观察入选者的踝-臂血压比值（ABI）、颈动脉内中膜厚度（IMT）,同时均测定体重指数、腰臀围比值、心脏LVEF、E/A、空腹血糖、血脂四项等临场指标。结果正常高值组的甘油三酯（TG）和低密度脂蛋白胆固醇（LDL-C）比正常对照组高（P〈0.05）,其高密度脂蛋白胆固醇（HDL-C）比正常组低（P〈0.05）;LVEF在两组之间无显著差异（P〉0.05）;正常高值组的ABI、颈动脉IMT高于正常对照组,但其E/A低于正常对照组（均为P〈0.05）。结论正常高值血压者不仅存在血脂代谢异常及心脏舒张功能的下降,同时也存在血管结构的变化。

Vascular structure changes in high-normal blood pressure persons by non-invasive examination

Objective To explore the vascular changes in in high-normal blood pressure persons by non-invasive examination.Methods 150 subjects were divided into two groups：high-normal blood pressure group（n=90）and control group（n=60）,and all objectives were examined Ankle-Brachial Index（ABI） by non-invasive method,meanwhile,the Intima-media thickness（IMT）,BMI,Waist-hip ratio,LVEF,E/A,Fasting blood glucose,four lipid were also detected.Results The level of Triglyceride and low-density lipoprotein cholesterol（LDL-C） in the high-normal blood pressure group were higher than the control group,but the high-density lipoprotein cholesterol（HDL-C）in the high-normal blood pressure group were smaller than that of the control group（P0.05）;the level of LVEF was no significant difference in the two groups,but,the level of E/A in the high-normal blood pressure group were smaller than those of the control group;More importantly,the level of ABI and IMT in the High-normal blood pressure group were higher than those of the control group.Conclusion Not only the dyslipidemia and the decline in diastolic function exist High-normal blood pressure persons,but also the vascular changes exist those pesons.