硅胶所致纤维包膜移植后的转归

目的:研究硅胶所致纤维包膜在移植后的转归,以验证其作为自体移植物的可能性和对隆乳术包膜挛缩是否有必要切除包膜。方法:20只白色SD大鼠,四肢皮下分别埋置硅胶片,1个月后取出硅胶片并将已形成的纤维包膜移植至其他处或留于原位,于移植后3d、2周,1个月、3个月观察其组织结构、纤维构成和吸收情况。结果:移植后随着时间延长纤维包膜的厚度、强度、阳性面积率均有所下降,有一定程度的吸收,留于原位的吸收较多,异位移植的吸收较少,两者比较有显著差异(P<0.05)。纤维包膜切碎组吸收最少,与未切碎组比较有显著差异(P<0.05)。结论:硅胶所致纤维包膜,在硅胶取出后留于原位可逐渐被吸收,故隆乳术后的挛缩包膜没有必要切除;包膜异位移植后吸收较少,其作为自体移植物有应用前景。

The Fate of the Fibrous Capsule Caused by Silicone after It Being Transplanted

Objective:To investigate the fate of the fibrous capsule caused by silicone gel after it being transplanted.Methods:Silicone gels were put under the skin of four legs in 20 SD rats,and 1 month later the silicone gel was removed and the fibrous capsule was left in the site or transplanted in the other site.Their histological traits,fibrous structure and the rate of the resorbtion was studied respectively on 3 days,2 weeks,1 month,3 months.Results:The intensity,thickness and positive area were decreased as the time relapsed.The resorption rate was lower in the transplant group than the group which still remained in the same site,their difference was significant(P<0.05).The lowest resorption group was which capsule diced.There was significant difference when compared with the other 4 groups.Conclusion:Silicone gel as the foreign body can induce the formation of the fibrous capsule,which can be transplanted as a autogenous graft.Breast capsule caused by the breast implant are needless to be removed together with the implant.