| 微基因修饰雪旺氏细胞移植对脊髓损伤中枢传导功能的作用 |
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| 引用本文： | 陈礼刚,高立达,周虎田,曾凡俊,毛伯镛,李讯,卢敏. 微基因修饰雪旺氏细胞移植对脊髓损伤中枢传导功能的作用[J]. 中国组织工程研究与临床康复, 2001, 5(10): 151 |
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| 作者姓名： | 陈礼刚 高立达 周虎田 曾凡俊 毛伯镛 李讯 卢敏 |
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| 作者单位： | CHEN Li-gang（Chengdu General Hospital of Chengdu Military Command,Chendu 610083, China;） ZHOU Hu-tian（Chengdu General Hospital of Chengdu Military Command,Chendu 610083, China;） ZEN Fan-jun（Chengdu General Hospital of Chengdu Military Command,Chendu 610083, China;） LIXun（Chengdu General Hospital of Chengdu Military Command,Chendu 610083, China;） GAO Li-da（lst Affiliated Hospital of West China University ofMedical Science） MAO Bo-yong（lst Affiliated Hospital of West China University ofMedical Science） LUMin（lst Affiliated Hospital of West China University ofMedical Science） |
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| 修稿时间： | 2001-01-01 |
Effect of MicrogenepSVPoMcat Implantation to Modify Genetically Schwann Cells on Central Conduction Functionafter Spinal Cord Injury |
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| CHEN Li-gang,Zhou Hu-tian,ZEN Fan-jun,LIXun,GAO Li-da,MAO Bo-yong,LUMin. Effect of MicrogenepSVPoMcat Implantation to Modify Genetically Schwann Cells on Central Conduction Functionafter Spinal Cord Injury[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2001, 5(10): 151 |
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| Authors: | CHEN Li-gang Zhou Hu-tian ZEN Fan-jun LIXun GAO Li-da MAO Bo-yong LUMin |
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| Abstract: | Objective To approach the effect of microgene pSVPoMcat to modify genetically Schwann cells (SC) on central conduction functionafter spinal cord injury (SCI) . Method Experimental animals were divided into three groups: the group of microgene pSVPoMcat implanted to genetically modify SC (group A), SC implanted group (group B), and the control group (group C). The cortical somatasensory evoked potentials (CESP) and combined behavioral score (CBS) were continuous monitored from operation second week to twelfth week Result The result showed that the peak latency and peak amplitudes of group A, B have a recovery tendency and it was constant with CBS. Conclusion We concluded that the microgene pSVPoMcat to modify genetically Sc may play a promotion role in recovery of central conduction function after SCI. |
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