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| 结核病实验室诊断研究进展 | |
| 引用本文： | 马爱静,赵雁林. 结核病实验室诊断研究进展[J]. 中华临床实验室管理电子杂志, 2016, 4(3): 153-158. DOI: 10.3877/cma.j.issn.2095-5820.2016.03.006 |
| 作者姓名： | 马爱静 赵雁林 |
| 作者单位： | 1. 102206 北京，中国疾病预防控制中心国家结核病参比实验室 |
| 基金项目： | 国家十二五传染病重大专项资助课题(2015ZX100030002) |
| 摘 要： | 结核病(tuberculosis, TB)是我国重点控制的重大传染性疾病之一。潜伏性结核分枝杆菌(Mycobacterium tuberculosis, MTB)感染和耐药结核病的非典型临床表现，导致TB的防治难度增加。早期准确诊断是TB正确有效治疗的基础和前提，也是降低TB传播的有效措施。随着分子生物学和免疫学的迅速发展，MTB病原学检查和药物敏感试验的时间极大地缩短。现对MTB的实验室诊断及新兴诊断技术进展阐述如下。 |
| 关 键 词： | 结核病 分子诊断 免疫学检查 |
| 收稿时间： | 2016-08-14 |
Progress in the laboratory diagnosis of tuberculosis |
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| Aijing Ma,Yanlin Zhao. Progress in the laboratory diagnosis of tuberculosis[J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2016, 4(3): 153-158. DOI: 10.3877/cma.j.issn.2095-5820.2016.03.006 | |
| Authors: | Aijing Ma Yanlin Zhao |
| Affiliation: | 1. National Tuberculosis Reference Laboratory, Chinese Center for Disease Control and Prevention, Beijing 102206, China |
| Abstract: | Tuberculosis (TB) is one of the major infectious diseases in China. The atypical clinical manifestations of latent mycobacterium tuberculosis (MTB) infection and drug-resistant tuberculosis led to increased difficulty in TB prevention and treatment. Early and accurate diagnosis is the basis and prerequisite for the correct treatment of TB and is also an effective way to reduce transmission. With the rapid development of molecular biology and immunology, the time for MTB pathogen examination and drug sensitivity test has been greatly shortened. The clinical and laboratory diagnosis as well as the development of new diagnostic techniques of MTB are described below. |
| Keywords: | Tuberculosis Molecular diagnostics Immunological examination |
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